White pharmaceutical pills in a bottle on a wooden table

SYLOID® FP Silica and XDP Silica

Multifunctional Excipient for Pharmaceutical & Nutraceutical Formulations

Grace SYLOID® FP and XDP Silica offers efficiency and performance in many pharmaceutical and nutraceutical applications, helping to solve powder flow and caking challenges. Manufactured in Germany, SYLOID® FP and XDP Silica are engineered hydrated silicon dioxides produced under controlled conditions, meeting EP,/EC, USP/NF, Health Canada, and ANVISA requirements and offering high chemical purity and performance.

Univar Solutions can support your pharmaceutical excipient needs through a global network of credentialed distribution centers across North America, Europe (Benelux, France, Germany, CEE, Spain, Portugal, Switzerland, UK and Ireland) and Latin America. Our dedicated pharma ingredients team has the technical expertise to help you navigate the research, development, and commercialization phases of your pharmaceutical or nutraceutical product journey.

Choose the right Syloid® FP Silica and XDP Silica for your application

GRADE	SYLOID 244FP	SYLOID 72FP	SYLOID AL-1FP	SYLOID XDP 3050	SYLOID XDP 3150
FREE FLOW	****	*****	***	***	***
ANTI-CAKING	*****	****	*	**	**
ANTI STATIC	*****	**	*	***	***
TABLETTING	*****	**	**	*****	*****
SUSPENSION	*****	*	****	**	**
MOISTURE	*****	*	******	***	***
ABSORBENT	*****	**	***	****	****
CARRIER	***	*	***	*****	*****
SOLID DISPERSION	***	***	***	*****	*****
DUST REDUCTION	***	***	***	*****	*****

Product Information

Applications, Benefits & Characteristics

Applications

Glidant
Forms layer around bulk powder, ball bearing affect
Helps achieve improved powder flow and minimize sticking and agglomeration
Improves compression rates and consistency of compression
Increases active uniformity
Active Carrying
High porosity/oil absorption increases absorptive capacity for oils and water
Liquid ingredients can be converted into free-flowing powders
Increased advantages for high doses of API in oral suspensions and tablets
Tabletting
Consistent compression
Improved hardness/structural stability
Enhanced coating
Improved dissolution
Lotions
Viscosity modifiers for topicals and semi-solids with load levels up to 25%
Matting agent
Improves and protects powder from agglomeration
Exfoliation
Fragrance and active carrying

Characteristics

Meets EP, USP/NF, JP Monographs
Meet EU Regulation No. 231/2012 for E 551 , Food Chemical Codex, Japan’ s Specification on Standard for Food Processing Aids, Silicon Dioxide
ICH Guideline on Elemental Impurities Q3D
Formed using a gelation process; washed, sized, and dried to a fine dry powder
Resilient structure resistant to grind
High density, lower dusting
High porosity for enhanced adsorptive capacity
Pores integral to the structure
Narrow pore structure
Easy to incorporate actives, providing more uniform dispersion of actives and improved content uniformity